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4. Chen, HW; Xue, J; Churikov, D; Hass, EP; Shi, SH; Lemon, LD; Luciano, P; Bertuch, AA; Zappulla, DC; Geli, V; Wu, J; Lei, M.Structural Insights into Yeast Telomerase Recruitment to Telomeres.CELL.38.637
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6. Xia, L; Wang, XR; Wei, R; Yan, JS; Chen, GQ; Lu, Y.Sumoylation of Pyruvate Kinase M2 Inhibits Myeloid Differentiation in Hematopoietic Cells.BLOOD.17.794
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10. Liu, JY; Duan, ZB; Guo, WJ; Zeng, L; Wu, YD; Chen, YL; Tai, F; Wang, YF; Lin, YW; Zhang, Q; He, YL; Deng, J; Stewart, RL; Wang, C; Lin, PC; Ghaffari, S; Evers, BM; Liu, SL; Zhou, MM; Zhou, BP; Shi, J.Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.NATURE COMMUNICATIONS.12.121
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12. Yu, XY; Lao, YM; Teng, XL; Li, S; Zhou, Y; Wang, FX; Guo, XW; Deng, SY; Chang, YZ; Wu, XF; Liu, ZD; Chen, L; Lu, LM; Cheng, JK; Li, B; Su, B; Jiang, J; Li, HB; Huang, CX; Yi, J; Zou, Q.SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.NATURE COMMUNICATIONS.12.121
13. Shen, SM; Ji, Y; Zhang, C; Dong, SS; Yang, S; Xiong, Z; Ge, MK; Yu, Y; Xia, L; Guo, M; Cheng, JK; Liu, JL; Yu, JX; Chen, GQ.Nuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role.NATURE COMMUNICATIONS.12.121
14. Wu, RF; Zeng, JR; Yuan, J; Deng, XJ; Huang, Y; Chen, LN; Zhang, P; Feng, H; Liu, ZX; Wang, ZJ; Gao, XF; Wu, HJ; Wang, HL; Su, YW; Zhao, M; Lu, QJ.MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.JOURNAL OF CLINICAL INVESTIGATION.11.864
15. Yang, FM; Zuo, Y; Zhou, W; Xia, C; Hahm, B; Sullivan, M; Cheng, JK; Chang, HM; Yeh, ETH.sNASP inhibits TLR signaling to regulate immune response in sepsis.JOURNAL OF CLINICAL INVESTIGATION.11.864
16. Zhang, YP; Xia, FZ; Liu, XY; Yu, Z; Xie, L; Liu, LG; Chen, CQ; Jiang, HS; Hao, XX; He, XX; Zhang, FF; Gu, H; Zhu, J; Bai, HT; Zhang, CC; Chen, GQ; Zheng, JK.JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/beta-catenin/CCND1 signaling.JOURNAL OF CLINICAL INVESTIGATION.11.864
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18. Huang, M; Song, K; Liu, XY; Lu, SY; Shen, QC; Wang, RX; Gao, JZ; Hong, YY; Li, Q; Ni, D; Xu, JR; Chen, GQ; Zhang, J.AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses.NUCLEIC ACIDS RESEARCH.11.502
19. Du, YZ; Hou, GF; Zhang, HL; Dou, JZ; He, JF; Guo, YM; Li, L; Chen, R; Wang, YL; Deng, R; Huang, J; JIang, B; Xu, M; Cheng, JK; Chen, GQ; Zhao, X; Yu, JX.SUMOylation of the m(6)A-RNA methyltransferase METTL3 modulates its function.NUCLEIC ACIDS RESEARCH.11.502
20. Lin, SZ; Xing, HP; Zang, TT; Ruan, X; Wo, LL; He, M.Sirtuins in mitochondrial stress: Indispensable helpers behind the scenes.AGEING RESEARCH REVIEWS.10.616
21. Zhao, Y; Wang, K; Chen, DY; Fan, BY; Xu, Y; Ye, YF; Wang, JB; Chen, J; Huang, CJ.Development of microfluidic impedance cytometry enabling the quantification of specific membrane capacitance and cytoplasm conductivity from 100,000 single cells.BIOSENSORS & BIOELECTRONICS.10.257
22. Peng, YJ; Yu, H; Hao, XX; Dong, WJ; Yin, XJ; Lin, MH; Zheng, JK; Zhou, BO.Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty.EMBO JOURNAL.9.889
23. Ning, NN; Yu, YM; Wu, M; Zhang, RH; Zhang, T; Zhu, CJ; Huang, L; Yun, CH; Benes, CH; Zhang, JM; Deng, XM; Chen, Q; Ren, RB.A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors.CANCER RESEARCH.9.727
24. Wei, B; Huang, C; Liu, B; Wang, Y; Xia, NS; Fan, QJ; Chen, GQ; Cheng, JK.Mitotic Phosphorylation of SENP3 Regulates DeSUMOylation of Chromosome-Associated Proteins and Chromosome Stability.CANCER RESEARCH.9.727
25. Ahmed, L; Zhang, YT; Block, E; Buehl, M; Corr, MJ; Cormanich, RA; Gundala, S; Matsunami, H; O'Hagan, D; Ozbil, M; Pan, Y; Sekharan, S; Ten, N; Wang, MG; Yang, MY; Zhang, QZ; Zhang, RN; Batista, VS; Zhuang, HY.Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds .PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.9.412
26. Kuser-Abali, G; Gong, L; Yan, JW; Liu, QQ; Zeng, WQ; Williamson, A; Lim, CB; Molloy, ME; Little, JB; Huang, L; Yuan, ZM.An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.9.412
27. Liu, XD; Zhu, XN; Halford, MM; Xu, TL; Henkemeyer, M; Xu, NJ.Retrograde regulation of mossy fiber axon targeting and terminal maturation via postsynaptic Lnx1.JOURNAL OF CELL BIOLOGY.8.811
28. Shangguan, CF; Gan, GF; Zhang, JY; Wu, JL; Miao, Y; Zhang, M; Li, B; Mi, J.Cancer-associated fibroblasts enhance tumor F-18-FDG uptake and contribute to the intratumor heterogeneity of PET-CT.THERANOSTICS.8.579
29. Liu, XY; Zhang, FF; Zhang, YP; Li, X; Chen, CQ; Zhou, MY; Yu, Z; Liu, YX; Zhao, YZ; Hao, XX; Tang, YB; Zhu, L; Liu, LG; Xie, L; Gu, H; Shao, HF; Xia, FZ; Yin, CR; Tao, MF; Xie, JJ; Zhang, CC; Yang, Y; Sun, HP; Chen, GQ; Zheng, JK.PPM1K Regulates Hematopoiesis and Leukemogenesis through CDC20-Mediated Ubiquitination of MEIS1 and p21.CELL REPORTS.8.109
30. Meng, W; Wang, BC; Mao, WW; Wang, JJ; Zhao, Y; Li, QF; Zhang, CR; Tang, YJ; Ma, J.Enhanced efficacy of histone deacetylase inhibitor combined with bromodomain inhibitor in glioblastoma.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH.7.068
31. Tang, C; Li, MH; Chen, YL; Sun, HY; Liu, SL; Zheng, WW; Zhang, MY; Li, H; Fu, W; Zhang, WJ; Liang, AB; Tang, ZH; Hong, DL; Zhou, BS; Duan, CW.Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH.7.068
32. Zu, LD; Peng, XC; Zeng, Z; Wang, JL; Meng, LL; Shen, WW; Hu, CT; Yang, Y; Fu, GH.Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH.7.068
33. Ran, H; Zhu, YM; Deng, RY; Zhang, Q; Liu, XS; Feng, M; Zhong, J; Lin, SH; Tong, XM; Su, Q.Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH.7.068
34. Xu, YY; Ouyang, XX; Yan, LC; Zhang, ML; Hu, ZL; Gu, JM; Fan, XM; Zhang, L; Zhang, JF; Xue, S; Chen, GQ; Su, B; Liu, JL Sin1 .(Stress-Activated Protein Kinase-Interacting Protein) Regulates Ischemia-Induced Microthrombosis Through Integrin IIb3-Mediated Outside-In Signaling and Hypoxia Responses in Platelets.ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY.6.604
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36. Yang, XY; Zhong, J; Zhang, QF; Qian, JX; Song, K; Ruan, C; Xu, JR; Ding, K; Zhang, J.Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction .JOURNAL OF MEDICINAL CHEMISTRY.6.205
37. Wang, J; Tan, MY; Ge, JF; Zhang, P; Zhong, J; Tao, L; Wang, Q; Tong, XM; Qiu, JX.Lysosomal acid lipase promotes cholesterol ester metabolism and drives clear cell renal cell carcinoma progression.CELL PROLIFERATION.5.753
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39. Liu, SL; Shi, L; Wang, Y; Ye, DX; Ju, HY; Ma, HL; Yang, WY; Wan, YN; Hu, JZ; Deng, J; Zhang, ZY.Stabilization of Slug by NF-kappa B is Essential for TNF-alpha -Induced Migration and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma Cells.CELLULAR PHYSIOLOGY AND BIOCHEMISTRY.5.5
40. Wang, YY; Tang, Y; Hang, HF; Wang, MM; Pang, YY; Yu, YH; Wu, Y; Zhu, Q.cAMP induces cell apoptosis in multiple myeloma and overcomes bortezomib resistance.AMERICAN JOURNAL OF CANCER RESEARCH.5.177
41. Li, Y; Pang, Z; Dong, XR; Liao, XD; Deng, HY; Liao, CH; Liao, YH; Chen, GQ; Huang, L.MUC1 induces M2 type macrophage influx during postpartum mammary gland involution and triggers breast cancer.ONCOTARGET.5.168
42. Zhao, WH; Xiao, SX; Li, HJ; Zheng, TT; Huang, J; Hu, R; Zhang, BH; Liu, XG; Huang, GH.MaPK Phosphatase-1 Deficiency exacerbates the severity of imiquimod-induced Psoriasiform skin Disease.FRONTIERS IN IMMUNOLOGY.5.085
43. Jing, B; Liu, M; Yang, L; Cai, HY; Chen, JB; Li, ZX; Kou, X; Wu, YZ; Qin, DJ; Zhou, L; Jin, J; Lei, H; Xu, HZ; Wang, WW; Wu, YL.Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro.ACTA PHARMACOLOGICA SINICA .5.064
44. Li, S; Jang, H; Zhang, J;. Nussinov, R Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling.STRUCTURE.4.862
45. Tong, XM; Li, B.A role of IL-25, a sibling of IL-17, in triggering psoriatic skin inflammation.SCIENCE CHINA-LIFE SCIENCES.4.611
46. Wang, YM; Liao, XD; Ye, Q; Huang, L .Clinic implication of MUC1 O-glycosylation and C1GALT1 in esophagus squamous cell carcinoma.SCIENCE CHINA-LIFE SCIENCES.4.611
47. Ni, D; Liu, DY; Zhang, J; Lu, SY.Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85 Regulatory Subunit of PI3K: Implication for PI3K Activation by Calmodulin.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.4.556
48. Sun, J; Hu, QW; Peng, H; Peng, C; Zhou, LH; Lu, JS; Huang, CX.The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.JOURNAL OF BIOLOGICAL CHEMISTRY.4.238
49. Miao, S; Zhang, RY; Wang, W; Wang, HB; Meng, LL; Zu, LD; Fu, GH.Overexpression of dedicator of cytokinesis 2 correlates with good prognosis in colorectal cancer associated with more prominent CD8(+) lymphocytes infiltration: a colorectal cancer analysis.JOURNAL OF CELLULAR BIOCHEMISTRY.4.237
50. Xu, ZH; Zhou, AP; Wu, JW; Zhou, AW; Li, J; Zhang, SL; Wu, WJ; Karakousis, PC; Yao, YF.Transcriptional Approach for Decoding the Mechanism of rpoC Compensatory Mutations for the Fitness Cost in Rifampicin-Resistant Mycobacterium tuberculosis.FRONTIERS IN MICROBIOLOGY.4.236
51. Wang, YY; Wu, LL; Cai, HY; Lei, H; Ma, CM; Yang, L; Xu, HZ; Zhu, Q; Yao, ZJ; Wu, YL.Sinomenine derivative YL064: a novel STAT3 inhibitor with promising anti-myeloma activity.CELL DEATH & DISEASE.4.114
52. Wang, QY; Zhou, CX; Zhan, MN; Tang, J; Wang, CL; Ma, CN; He, M; Chen, GQ; He, JR; Zhao, Q.MiR-133b targets Sox9 to control pathogenesis and metastasis of breast cancer.CELL DEATH & DISEASE.4.114
53. Jing, B; Jin, J; Xiang, RF; Liu, M; Yang, L; Tong, Y; Xiao, XH; Lei, H; Liu, W; Xu, HZ; Deng, J; Zhou, L; Wu, YL.Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition.CELL DEATH & DISEASE.4.114
54. Li, Z; Li, SP; Li, RY; Zhu, H; Liu, X; Guo, XL; Cai, JJ; Bai, F; Chen, GQ; Hong, DL.Leukaemic alterations of IKZF1 prime stemness and malignancy programs in human lymphocytes.CELL DEATH & DISEASE.4.114
55. Chen, Y; Li, Z; Xu, Z; Tang, HY; Guo, WX; Sun, XX; Zhang, WJ; Zhang, J; Wan, XP; Jiang, Y; Mao, ZY.Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy.CELL DEATH & DISEASE.4.114
56. Wang, YY; Wu, LL; Cai, HY; Lei, H; Ma, CM; Yang, L; Xu, HZ; Zhu, Q; Yao, ZJ; Wu, YL.YL064 directly inhibits STAT3 activity to induce apoptosis of multiple myeloma cells.CELL DEATH DISCOVERY.4.114
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58. An, XF; Zhang, L; Yao, QM; Li, L; Wang, B; Zhang, JS; He, M; Zhang, JN.The receptor for advanced glycation endproducts mediates podocyte heparanase expression through NF-kappa B signaling pathway.MOLECULAR AND CELLULAR ENDOCRINOLOGY.3.871
59. Lue, YH; Gao, C; Swerdloff, R; Hoang, J; Avetisyan, R; Jia, Y; Rao, M; Ren, SX; Atienza, V; Yu, JY; Zhang, Y; Chen, MP; Song, Y; Wang, YB; Wang, C.Humanin analog enhances the protective effect of dexrazoxane against doxorubicin-induced cardiotoxicity.AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY.3.864
60. Yue, ZW; Xiao, XH; Wu, JB; Zhou, XZ; Liu, WL; Liu, YX; Li, HH; Chen, GQ; Wu, YL; Lei, XG.ent-Jungermannenone C Triggers Reactive Oxygen Species-Dependent Cell Differentiation in Leukemia Cells.JOURNAL OF NATURAL PRODUCTS.3.782
61. Wang, Y; Hu, JZ; Wang, YA; Ye, WM; Zhang, XK; Ju, HY; Xu, DL; Liu, L; Ye, DX; Zhang, L; Zhu, DW; Deng, J; Zhang, ZY; Liu, SL.EGFR activation induced Snail-dependent EMT and myc-dependent PD-L1 in human salivary adenoid cystic carcinoma cells.CELL CYCLE.3.699
62. Tang, CX; Lei, H; Zhang, JF; Liu, M; Jin, J; Luo, H; Xu, HZ; Wu, YL.Montelukast inhibits hypoxia inducible factor-1 alpha translation in prostate cancer cells.CANCER BIOLOGY & THERAPY.3.659
63. Wu, JJ; Guo, WZ; Wen, DH; Hou, GY; Zhou, AP; Wu, WJ.Deubiquitination and stabilization of programmed cell death ligand 1 by ubiquitin-specific peptidase 9, X-linked in oral squamous cell carcinoma.CANCER MEDICINE.3.491
64. Luo, GT; Xia, X; Wang, XF; Zhang, KD; Cao, J; Jiang, T; Zhao, Q; Qiu, ZJ.miR-301a plays a pivotal role in hypoxia-induced gemcitabine resistance in pancreatic cancer.EXPERIMENTAL CELL RESEARCH.3.383
65. Gong, XF; Yu, AL; Tang, J; Wang, CL; He, JR; Chen, GQ; Zhao, Q; He, M; Zhou, CX.MicroRNA-630 inhibits breast cancer progression by directly targeting BMI1.EXPERIMENTAL CELL RESEARCH. 3.383
66. Hu, ZL; Zou, Q; Su, B.Regulation of T cell immunity by cellular metabolism.FRONTIERS OF MEDICINE.3.297
67. Duan, J; Liu, XS; Wang, HL; Guo, SW.The M2a macrophage subset may be critically involved in the fibrogenesis of endometriosis in mice.REPRODUCTIVE BIOMEDICINE ONLINE.3.218
68. Meng, LL; Wang, JL; Xu, SP; Zu, LD; Yan, ZW; Zhang, JB; Han, YQ; Fu, GH.Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling.BMC CANCER.3.15
69. Xie, B; Liu, XY; Yang, J; Cheng, JK; Gu, JM; Xue, S.PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPAR SUMOylation.BMC CELL BIOLOGY.3.066
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71. Lei, H; Wang, WW; Wu, YL.Targeting oncoproteins for degradation by small molecules in myeloid leukemia.LEUKEMIA & LYMPHOMA.2.969
72. Meng, W; Wang, JJ; Wang, BC; Liu, F; Li, M; Zhao, Y; Zhang, CR; Li, QF; Chen, JX; Zhang, LY; Tang, YJ; Ma, J.CDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo.CANCER MANAGEMENT AND RESEARCH.2.886
73. Wang, GQ; Zhang, MZ; Jang, H; Lu, SY; Lin, SZ; Chen, GQ; Nussinov, R; Zhang, J; Gaponenko, V.Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit.BIOCHEMISTRY.2.865
74. Zhang, MZ; Li, ZG; Wang, GQ; Jang, H; Sacks, DB; Zhang, J; Gaponenko, V; Nussinov, R.Calmodulin (CaM) Activates PI3K alpha by Targeting the Soft CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha.JOURNAL OF PHYSICAL CHEMISTRY B.2.857
75. Zhang, XC; Shi, Y; Song, LJ; Shen, C; Cai, Q; Zhang, Z; Wu, J; Fu, GH; Shen, WW.Identification of mutations in patients with acquired pure red cell aplasia.ACTA BIOCHIMICA ET BIOPHYSICA SINICA.2.836
76. Zhang, XM; Song, LJ; Shen, J; Yue, H; Han, YQ; Yang, CL; Liu, SY; Deng, JW; Jiang, Y; Fu, GH; Shen, WW.Prognostic and predictive values of immune infiltrate in patients with head and neck squamous cell carcinoma.HUMAN PATHOLOGY.2.735
77. Zhang, RN; Pan, Y; Ahmed, L; Block, E; Zhang, YT; Batista, VS; Zhuang, HY.A Multispecific Investigation of the Metal Effect in Mammalian Odorant Receptors for Sulfur-Containing Compounds.CHEMICAL SENSES.2.261
78. Lei, H; Yang, L; Zhou, L; Tong, Y; Wu, YL.Targeting acute myeloid leukemia CD34(+) stem/progenitor cells with small molecule inhibitor MK-8776.LEUKEMIA RESEARCH.2.214
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