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Lv M, Shi T, Mao X, Li X, Chen Y, Zhu J, Ni S, Shen X, Jiang H, Li J, Zhang J, Huang J.1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: a novel cyclophilin A allosteric activator.Biochem Biophys Res Commun. 2012;425(4):938-43. 6. Chen Y, Wen D, Huang Z, Huang M, Luo Y, Liu B, Lu H, Wu Y, Peng Y, Zhang J.2-(4-Chlorophenyl)-2-oxoethyl 4-benzamidobenzoate derivatives, a novel class of SENP1 inhibitors: Virtual screening, synthesis and biological evaluation.Bioorg Med Chem Lett. 2012;22(22):6867-70. 7. Suo WH, Zhang N, Wu PP, Zhao L, Song LJ, Shen WW, Zheng L, Tao J, Long XD, Fu GH.Anti-tumour effects of small interfering RNA targeting anion exchanger 1 in experimental gastric cancer.Br J Pharmacol. 2012;165(1):135-47. 8. Jiang Z, Fan Q, Zhang Z, Zou Y, Cai R, Wang Q, Zuo Y, Cheng J.SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation.Cell Cycle. 2012;11(6):1118-22. 9. Sun H, Wang Y.Prostaglandin E2 in remote control of myocardial remodeling.Circulation. 2012;125(23):2818-20. 10. Zhao S, Ma CM, Liu CX, Wei W, Sun Y, Yan H, Wu YL.Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells.Int J Mol Med. 2012;30(4):939-44. 11. Zhou M, Lu G, Gao C, Wang Y, Sun H.Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm).J Biol Chem. 2012;287(28):23397-406. 12. Wu L, Pan Y, Chen GQ, Matsunami H, Zhuang H.Receptor-transporting protein 1 short (RTP1S) mediates translocation and activation of odorant receptors by acting through multiple steps.J Biol Chem. 2012;287(26):22287-94. 13. Lu S, Huang W, Li X, Huang Z, Liu X, Chen Y, Shi T, Zhang J.Insights into the role of magnesium triad in myo-inositol monophosphatase: metal mechanism, substrate binding, and lithium therapy.J Chem Inf Model. 2012;52(9):2398-409. 14. Wang Q, Zheng M, Huang Z, Liu X, Zhou H, Chen Y, Shi T, Zhang J.Toward understanding the molecular basis for chemical allosteric modulator design.J Mol Graph Model. 2012;38:324-33. 15. Song LJ, Liu RJ, Zeng Z, Alper SL, Cui HJ, Lu Y, Zheng L, Yan ZW, Fu GH.Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2, and P-ERK.J Mol Med (Berl). 2012;90(6):707-18. 16. Liu B, Zheng Y, Wang TD, Xu HZ, Xia L, Zhang J, Wu YL, Chen GQ, Wang LS.Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.J Proteome Res. 2012;11(3):1773-81. 17. Kua HY, Liu H, Leong WF, Li L, Jia D, Ma G, Hu Y, Wang X, Chau JF, Chen YG, Mishina Y, Boast S, Yeh J, Xia L, Chen GQ, He L, Goff SP, Li B.c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression.Nat Cell Biol. 2012;14(7):727-37. 18. Liu CX, Yin QQ, Zhou HC, Wu YL, Pu JX, Xia L, Liu W, Huang X, Jiang T, Wu MX, He LC, Zhao YX, Wang XL, Xiao WL, Chen HZ, Zhao Q, Zhou AW, Wang LS, Sun HD, Chen GQ.Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells.Nat Chem Biol. 2012;8(5):486-93. 19. Huang J, Yan J, Zhang J, Zhu S, Wang Y, Shi T, Zhu C, Chen C, Liu X, Cheng J, Mustelin T, Feng GS, Chen G, Yu J.SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane.Nat Commun. 2012;3:911. 20. He LC, Gao FH, Xu HZ, Zhao S, Ma CM, Li J, Zhang S, Wu YL.Ikaros inhibits proliferation and, through upregulation of Slug, increases metastatic ability of ovarian serous adenocarcinoma cells.Oncol Rep. 2012;28(4):1399-405. 21. Sun H, Wang Y.Novel Ser/Thr protein phosphatases in cell death regulation.Physiology (Bethesda). 2012;27(1):43-52 22. Liu X, Liu B, Huang Z, Shi T, Chen Y, Zhang J.SPPS: a sequence-based method for predicting probability of protein-protein interaction partners.PLoS One. 2012;7(1):e30938 23. Duan X, Block E, Li Z, Connelly T, Zhang J, Huang Z, Su X, Pan Y, Wu L, Chi Q, Thomas S, Zhang S, Ma M, Matsunami H, Chen GQ, Zhuang H.Crucial role of copper in detection of metal-coordinating odorants.Proc Natl Acad Sci U S A. 2012;109(9):3492-7 24. Huang Z, Jiang H, Liu X, Chen Y, Wong J, Wang Q, Huang W, Shi T, Zhang J.HEMD: an integrated tool of human epigenetic enzymes and chemical modulators for therapeutics.PLoS One. 2012;7(6):e39917 25. Wang LS, Xia L, Shen SM, Zheng Y, Yu Y, Chen GQ.Dissecting cell death with proteomic scalpels.Proteomics. 2012;12(4-5):597-606 26. Wang Y, Yang J, Yi J.Redox sensing by proteins: oxidative modifications on cysteines and the consequent events.Antioxid Redox Signal. 2012;16(7):649-57 27. 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Huang X, Yan Y, Tu Y, Gatti J, Broze GJ Jr, Zhou A, Olson ST. Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z. Blood. 2012 Aug 23;120(8):1726-33. 32. Zhao S, Ma CM, Liu CX, Wei W, Liu B, Xu HZ, He LC, Yan Hua, Wu YL*. Autophagy inhibition enhances isobavachalcone induced cell death in multiple myeloma cells. Int J Mol Med, 2012, 30(4):939-44 33. Ping Wang, Juan Mei, Jing Tao, Ning Zhang, Hua Tian, Guo-Hui Fu. Effects of Helicobacter pylori on biological characteristics of gastric epithelial cells. Histol Histopathol .2012,27: 1079-1091 34. Liu W, Shen SM, Zhao XY, Chen GQ.Targeted genes and interacting proteins of hypoxia inducible factor-1.Int J Biochem Mol Biol. 2012;3(2):165-78 |