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当前位置>>科研成果
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Gu ZM, Wu YL, Zhou MY, Liu CX, Xu HZ, Yan H, Zhao Y, Huang Y, Sun HD, Chen GQ.Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction withATRAin myeloid leukemic cells.Blood. 2010;116(24):5289-97. |
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Weng Z, Li D, Zhang L, Chen J, Ruan C, Chen G, Gartner TK, Liu J.PTEN regulates collagen-induced platelet activation.Blood. 2010;116(14):2579-81. |
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Gao FH, Hu XH, Li W, Liu H, Zhang YJ, Guo ZY, Xu MH, Wang ST, Jiang B, Liu F, Zhao YZ, Fang Y, Chen FY, Wu YL.Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc.BMC Cancer. 2010;10:610. |
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Sun X, Cheng G, Hao M, Zheng J, Zhou X, Zhang J, Taichman RS, Pienta KJ, Wang J.CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression.Cancer Metastasis Rev. 2010 ;29(4):709-22. |
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Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R.Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis.Cancer Prev Res (Phila). 2010;3(4):424-37. |
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Shen SM, Yu Y, Wu YL, Cheng JK, Wang LS, Chen GQ.Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells.Carcinogenesis. 2010;31(3):419-26. |
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Zhao XY, Chen TT, Xia L, Guo M, Xu Y, Yue F, Jiang Y, Chen GQ, Zhao KW.Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells.Carcinogenesis. 2010;31(8):1367-75. |
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Duan XF, Wu YL, Xu HZ, Zhao M, Zhuang HY, Wang XD, Yan H, Chen GQ.Synergistic mitosis-arresting effects of arsenic trioxide and paclitaxel on human malignant lymphocytes.Chem Biol Interact. 2010;183(1):222-30. |
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Xu HZ, Huang Y, Wu YL, Zhao Y, Xiao WL, Lin QS, Sun HD, Dai W, Chen GQ.Pharicin A, a novel natural ent-kaurene diterpenoid, induces mitotic arrest and mitotic catastrophe of cancer cells by interfering with BubR1 function.Cell Cycle. 2010;9(14):2897-907. |
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Yan S, Sun X, Xiang B, Cang H, Kang X, Chen Y, Li H, Shi G, Yeh ET, Wang B, Wang X, Yi J.Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90.EMBO J. 2010;29(22):3773-86. |
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Wu YL, Zhou HC, Chen GQ.Molecular mechanisms of leukemia-associated protein degradation.Front Med China. 2010;4(4):363-70. |
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Xiao WL,Wu YL,Shang SZ,He F,Luo X,Yang GY,Pu JX,Chen GQ,Sun HD.Four New Nortriterpenoids from Schisandra lancifolia.Helvetica Chimica Acta.2010;93(10):1975-82 |
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Tian H, Zhang N, Suo WH, Wang T, Song LJ, Wu J, Liu Q, Shen WW, Fu GH.Gastrin suppresses the interdependent expression of p16 and anion exchanger 1 favoring growth inhibition of gastric cancer cells.Int J Cancer. 2010;127(6):1462-74. |
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Gao F, Tang Q, Yang P, Fang Y, Li W, Wu Y.Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells.Int J Lab Hematol. 2010;32(1 Pt 1):e114-22. |
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Xu Y, Zuo Y, Zhang H, Kang X, Yue F, Yi Z, Liu M, Yeh ET, Chen G, Cheng J.Induction of SENP1 in endothelial cells contributes to hypoxia-driven VEGF expression and angiogenesis.J Biol Chem. 2010;285(47):36682-8. |
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Han Y, Huang C, Sun X, Xiang B, Wang M, Yeh ET, Chen Y, Li H, Shi G, Cang H, Sun Y, Wang J, Wang W, Gao F, Yi J.SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.J Biol Chem. 2010;285(17):12906-15. |
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Zhao Y, Lu X, Yang CY, Huang Z, Fu W, Hou T, Zhang J.Computational modeling toward understanding agonist binding on dopamine 3.J Chem Inf Model. 2010;50(9):1633-43. |
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Azouz A, Wu YL, Hillion J, Tarkanyi I, Karniguian A, Aradi J, Lanotte M, Chen GQ, Chehna M, Ségal-Bendirdjian E.Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.Leukemia. 2010;24(3):613-22. |
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Wu SF, Huang Y, Hou JK, Yuan TT, Zhou CX, Zhang J, Chen GQ.The downregulation of onzin expression by PKCepsilon-ERK2 signaling and its potential role in AML cell differentiation.Leukemia. 2010;24(3):544-51. |
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Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET.SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.Mol Cell. 2010;38(2):191-201. |
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Wu J, Zhang YC, Suo WH, Liu XB, Shen WW, Tian H, Fu GH.Induction of anion exchanger-1 translation and its opposite roles in the carcinogenesis of gastric cancer cells and differentiation of K562 cells.Oncogene. 2010;29(13):1987-96. |
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Kang X, Li J, Zou Y, Yi J, Zhang H, Cao M, Yeh ET, Cheng J.PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxia.Oncogene. 2010;29(41):5568-78. |
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