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1: Wang D, Gu X, Ma X, Chen J, Zhang Q, Yu Z, Li J, Hu M, Tan X, Tang Y, Xu J,
Xu M, Song Q, Song H, Jiang G, Tang Z, Gao X, Chen H. Nanopolyphenol rejuvenates
microglial surveillance of multiple misfolded proteins through metabolic
reprogramming. Acta Pharm Sin B. 2023 Feb;13(2):834-851. doi:
10.1016/j.apsb.2022.07.014. Epub 2022 Jul 21. PMID: 36873190; PMCID: PMC9978858.

2: He Y, Su Y, Duan C, Wang S, He W, Zhang Y, An X, He M. Emerging role of aging
in the progression of NAFLD to HCC. Ageing Res Rev. 2023 Feb;84:101833. doi:
10.1016/j.arr.2022.101833. Epub 2022 Dec 22. PMID: 36565959.

3: Leng H, Zhang H, Li L, Zhang S, Wang Y, Chavda SJ, Galas-Filipowicz D, Lou H,
Ersek A, Morris EV, Sezgin E, Lee YH, Li Y, Lechuga-Vieco AV, Tian M, Mi JQ,
Yong K, Zhong Q, Edwards CM, Simon AK, Horwood NJ. Modulating glycosphingolipid
metabolism and autophagy improves outcomes in pre-clinical models of myeloma
bone disease. Nat Commun. 2022 Dec 22;13(1):7868. doi:
10.1038/s41467-022-35358-3. PMID: 36550101; PMCID: PMC9780346.

4: Fan Y, Huang C, Chen J, Chen Y, Wang Y, Yan Z, Yu W, Wu H, Yang Y, Nie L,
Huang S, Wang F, Wang H, Hua Y, Lyu Q, Kuang Y, Lei M. Mutations in CCIN cause
teratozoospermia and male infertility. Sci Bull (Beijing). 2022 Oct
31;67(20):2112-2123. doi: 10.1016/j.scib.2022.09.026. Epub 2022 Sep 26. PMID:
36546111.

5: Wang Z, Sun Y, Lou F, Bai J, Zhou H, Cai X, Sun L, Yin Q, Tang S, Wu Y, Fan
L, Xu Z, Wang H, Hu X, Wang H. Targeting the transcription factor HES1 by
L-menthol restores protein phosphatase 6 in keratinocytes in models of
psoriasis. Nat Commun. 2022 Dec 19;13(1):7815. doi: 10.1038/s41467-022-35565-y.
PMID: 36535970; PMCID: PMC9763329.

6: He X, Xu Y, Huang D, Yu Z, Yu J, Xie L, Liu L, Yu Y, Chen C, Wan J, Zhang Y,
Zheng J. P2X1 enhances leukemogenesis through PBX3-BCAT1 pathways. Leukemia.
2023 Feb;37(2):265-275. doi: 10.1038/s41375-022-01759-y. Epub 2022 Nov 23. PMID:
36418376; PMCID: PMC9898031.

7: Jiang Y, Wang J, Sun M, Zuo D, Wang H, Shen J, Jiang W, Mu H, Ma X, Yin F,
Lin J, Wang C, Yu S, Jiang L, Lv G, Liu F, Xue L, Tian K, Wang G, Zhou Z, Lv Y,
Wang Z, Zhang T, Xu J, Yang L, Zhao K, Sun W, Tang Y, Cai Z, Wang S, Hua Y.
Multi-omics analysis identifies osteosarcoma subtypes with distinct prognosis
indicating stratified treatment. Nat Commun. 2022 Nov 23;13(1):7207. doi:
10.1038/s41467-022-34689-5. PMID: 36418292; PMCID: PMC9684515.

8: Cui K, Li R, Zhang Y, Qiu Y, Zhao N, Cui Y, Wu W, Liu T, Xiao Z. Molecular
Planarization of Raman Probes to Avoid Background Interference for High-
Precision Intraoperative Imaging of Tumor Micrometastases and Lymph Nodes. Nano
Lett. 2022 Dec 14;22(23):9424-9433. doi: 10.1021/acs.nanolett.2c03416. Epub 2022
Nov 15. PMID: 36378880.

9: Han M, Li F, Zhang Y, Dai P, He J, Li Y, Zhu Y, Zheng J, Huang H, Bai F, Gao
D. FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine
prostate cancer. Cancer Cell. 2022 Nov 14;40(11):1306-1323.e8. doi:
10.1016/j.ccell.2022.10.011. Epub 2022 Nov 3. PMID: 36332622.

10: Zhou J, Zhang J, Tao L, Peng K, Zhang Q, Yan K, Luan J, Pan J, Su X, Sun J,
Zhang Z, Shen L. Up-regulation of BTN3A1 on CD14<sup>+</sup> cells promotes
Vγ9Vδ2 T cell activation in psoriasis. Proc Natl Acad Sci U S A. 2022
Nov;119(44):e2117523119. doi: 10.1073/pnas.2117523119. Epub 2022 Oct 26. PMID:
36288286; PMCID: PMC9636952.

11: Dong S, Xiao MZX, Liang Q. Modulation of cellular machineries by Zika virus-
encoded proteins. J Med Virol. 2023 Jan;95(1):e28243. doi: 10.1002/jmv.28243.
Epub 2022 Oct 28. PMID: 36262094.

12: Wang HL, Chen Y, Wang YQ, Tao EW, Tan J, Liu QQ, Li CM, Tong XM, Gao QY,
Hong J, Chen YX, Fang JY. Sirtuin5 protects colorectal cancer from DNA damage by
keeping nucleotide availability. Nat Commun. 2022 Oct 17;13(1):6121. doi:
10.1038/s41467-022-33903-8. PMID: 36253417; PMCID: PMC9576705.

13: Luo MY, Zhou Y, Gu WM, Wang C, Shen NX, Dong JK, Lei HM, Tang YB, Liang Q,
Zou JH, Xu L, Ma P, Zhuang G, Bi L, Xu L, Zhu L, Chen HZ, Shen Y. Metabolic and
Nonmetabolic Functions of PSAT1 Coordinate Signaling Cascades to Confer EGFR
Inhibitor Resistance and Drive Progression in Lung Adenocarcinoma. Cancer Res.
2022 Oct 4;82(19):3516-3531. doi: 10.1158/0008-5472.CAN-21-4074. PMID: 36193649.

14: Li Q, Yue T, Du X, Tang Z, Cui J, Wang W, Xia W, Ren B, Kan S, Li C, Wu C,
Niu X, Li B, Lin K, Luo J, Chen G, Wang Z. HSC70 mediated autophagic degradation
of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone
destruction. Cell Death Differ. 2023 Mar;30(3):647-659. doi:
10.1038/s41418-022-01068-y. Epub 2022 Oct 1. PMID: 36182990; PMCID: PMC9984420.

15: Wei D, Chen Y, Yu X, Lai YD, Xu W, Ji P, Yang Z, Chen E, Zhang X, Wang Y.
Comparable antigen-specific T cell responses in vaccinees with diverse humoral
immune responses after the primary and booster BBIBP-CorV vaccination. Emerg
Microbes Infect. 2022 Dec;11(1):2474-2484. doi: 10.1080/22221751.2022.2130101.
PMID: 36166417; PMCID: PMC9621266.

16: Liu Y, Zhou J, Li X, Zhang X, Shi J, Wang X, Li H, Miao S, Chen H, He X,
Dong L, Lee GR, Zheng J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB.
tRNA-m<sup>1</sup>A modification promotes T cell expansion via efficient MYC
protein synthesis. Nat Immunol. 2022 Oct;23(10):1433-1444. doi:
10.1038/s41590-022-01301-3. Epub 2022 Sep 22. PMID: 36138184.

17: Sun G, Gu Q, Zheng J, Cheng H, Cheng T. Emerging roles of extracellular
vesicles in normal and malignant hematopoiesis. J Clin Invest. 2022 Sep
15;132(18):e160840. doi: 10.1172/JCI160840. PMID: 36106632; PMCID: PMC9479752.

18: Yang Y, Zhang C, Song Y, Li Y, Li P, Huang M, Meng F, Zhang M. Small-
molecule activators specific to adenine base editors through blocking the
canonical TGF-β pathway. Nucleic Acids Res. 2022 Sep 23;50(17):9632-9646. doi:
10.1093/nar/gkac742. PMID: 36043443; PMCID: PMC9508813.

19: Zhong J, Guo Y, Lu S, Song K, Wang Y, Feng L, Zheng Z, Zhang Q, Wei J, Sang
P, Shi Y, Cai J, Chen G, Liu CY, Yang X, Zhang J. Rational design of a
sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors. Nat
Commun. 2022 Aug 24;13(1):4961. doi: 10.1038/s41467-022-32612-6. PMID: 36002443;
PMCID: PMC9402538.

20: Cheng L, Wang S, Peng C, Zou X, Yang C, Mei H, Li C, Su X, Xiao N, Ouyang Q,
Zhang M, Wang Q, Luo Y, Shen M, Qin Q, Wang H, Zhu W, Lu G, Lin G, Kuang Y, Chen
X. Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1/2a,
single-arm study. Signal Transduct Target Ther. 2022 Aug 5;7(1):263. doi:
10.1038/s41392-022-01059-y. PMID: 35927231; PMCID: PMC9352692.

21: Sun Y, Yan K, Wang Y, Xu C, Wang D, Zhou W, Guo S, Han Y, Tang L, Shao Y,
Shan S, Zhang QC, Tang Y, Zhang L, Xi Q. Context-dependent tumor-suppressive BMP
signaling in diffuse intrinsic pontine glioma regulates stemness through
epigenetic regulation of CXXC5. Nat Cancer. 2022 Sep;3(9):1105-1122. doi:
10.1038/s43018-022-00408-8. Epub 2022 Aug 1. PMID: 35915262.

22: Qiu Z, Guo W, Dong B, Wang Y, Deng P, Wang C, Liu J, Zhang Q, Grosschedl R,
Yu Z, Deng J, Wu Y. EBF1 promotes triple-negative breast cancer progression by
surveillance of the HIF1α pathway. Proc Natl Acad Sci U S A. 2022 Jul
12;119(28):e2119518119. doi: 10.1073/pnas.2119518119. Epub 2022 Jul 8. PMID:
35867755; PMCID: PMC9282371.

23: Lei H, Yang L, Wang Y, Zou Z, Liu M, Xu H, Wu Y. JOSD2 regulates PKM2
nuclear translocation and reduces acute myeloid leukemia progression. Exp
Hematol Oncol. 2022 Jul 14;11(1):42. doi: 10.1186/s40164-022-00295-w. PMID:
35836282; PMCID: PMC9281007.

24: Wang L, Wen X, Wang Z, Lin Z, Li C, Zhou H, Yu H, Li Y, Cheng Y, Chen Y, Lou
G, Pan J, Cao M. Ciliary transition zone proteins coordinate ciliary protein
composition and ectosome shedding. Nat Commun. 2022 Jul 9;13(1):3997. doi:
10.1038/s41467-022-31751-0. PMID: 35810181; PMCID: PMC9271036.

25: Gao S, Chen T, Wang Z, Ji P, Xu L, Cui W, Wang Y. Immuno-activated
mesenchymal stem cell living electrospun nanofibers for promoting diabetic wound
repair. J Nanobiotechnology. 2022 Jun 21;20(1):294. doi:
10.1186/s12951-022-01503-9. PMID: 35729570; PMCID: PMC9210587.

26: Yang C, Jin J, Yang Y, Sun H, Wu L, Shen M, Hong X, Li W, Lu L, Cao D, Wang
X, Sun J, Ye Y, Su B, Deng L. Androgen receptor-mediated CD8<sup>+</sup> T cell
stemness programs drive sex differences in antitumor immunity. Immunity. 2022
Jul 12;55(7):1268-1283.e9. doi: 10.1016/j.immuni.2022.05.012. Epub 2022 Jun 13.
Erratum in: Immunity. 2022 Sep 13;55(9):1747. PMID: 35700739.

27: Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y,
Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H,
Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH. Gremlin1 is a
therapeutically targetable FGFR1 ligand that regulates lineage plasticity and
castration resistance in prostate cancer. Nat Cancer. 2022 May;3(5):565-580.
doi: 10.1038/s43018-022-00380-3. Epub 2022 May 27. PMID: 35624341.

28: Yang X, Zhou J, Liu C, Qu Y, Wang W, Xiao MZX, Zhu F, Liu Z, Liang Q. KSHV-
encoded ORF45 activates human NLRP1 inflammasome. Nat Immunol. 2022
Jun;23(6):916-926. doi: 10.1038/s41590-022-01199-x. Epub 2022 May 26. PMID:
35618833.

29: Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y,
Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T,
Hu H, Hu Z, Xu H, Ye D, Yang H, Li B, Tong X. Non-oxidative pentose phosphate
pathway controls regulatory T cell function by integrating metabolism and
epigenetics. Nat Metab. 2022 May;4(5):559-574. doi: 10.1038/s42255-022-00575-z.
Epub 2022 May 23. PMID: 35606596.

30: Chen X, Xu Y, Chen Q, Zhang H, Zeng Y, Geng Y, Shen L, Li F, Chen L, Chen
GQ, Huang C, Liu J. The phosphatase PTEN links platelets with immune regulatory
functions of mouse T follicular helper cells. Nat Commun. 2022 May
19;13(1):2762. doi: 10.1038/s41467-022-30444-y. PMID: 35589797; PMCID:
PMC9120038.

31: Ding N, Wang K, Jiang H, Yang M, Zhang L, Fan X, Zou Q, Yu J, Dong H, Cheng
S, Xu Y, Liu J. AGK regulates the progression to NASH by affecting mitochondria
complex I function. Theranostics. 2022 Apr 4;12(7):3237-3250. doi:
10.7150/thno.69826. PMID: 35547757; PMCID: PMC9065199.

32: Zou HY, Guo L, Zhang B, Chen S, Wu XR, Liu XD, Xu XY, Li BY, Chen S, Xu NJ,
Sun S. Aberrant miR-339-5p/neuronatin signaling causes prodromal neuronal
calcium dyshomeostasis in mutant presenilin mice. J Clin Invest. 2022 Apr
15;132(8):e149160. doi: 10.1172/JCI149160. Erratum in: J Clin Invest. 2023 Feb
1;133(3): Erratum in: J Clin Invest. 2023 Feb 15;133(4): PMID: 35426376; PMCID:
PMC9012292.

33: Xu Y, Ding J. Endomembrane damage sensing by V-ATPase recruits ATG16L1 for
LC3 lipidation <i>in situ</i>. Autophagy. 2022 Nov;18(11):2751-2753. doi:
10.1080/15548627.2022.2062889. Epub 2022 Apr 12. PMID: 35410580; PMCID:
PMC9629116.

34: Zhao M, Wei H, Li C, Zhan R, Liu C, Gao J, Yi Y, Cui X, Shan W, Ji L, Pan B,
Cheng S, Song M, Sun H, Jiang H, Cai J, Garcia-Barrio MT, Chen YE, Meng X, Dong
E, Wang DW, Zheng L. Gut microbiota production of trimethyl-5-aminovaleric acid
reduces fatty acid oxidation and accelerates cardiac hypertrophy. Nat Commun.
2022 Apr 1;13(1):1757. doi: 10.1038/s41467-022-29060-7. PMID: 35365608; PMCID:
PMC8976029.

35: Song C, Shi J, Zhang P, Zhang Y, Xu J, Zhao L, Zhang R, Wang H, Chen H.
Immunotherapy for Alzheimer's disease: targeting β-amyloid and beyond. Transl
Neurodegener. 2022 Mar 18;11(1):18. doi: 10.1186/s40035-022-00292-3. PMID:
35300725; PMCID: PMC8932191.

36: Yan G, Li X, Zheng Z, Gao W, Chen C, Wang X, Cheng Z, Yu J, Zou G, Farooq
MZ, Zhu X, Zhu W, Zhong Q, Yan X. KAT7-mediated CANX (calnexin) crotonylation
regulates leucine-stimulated MTORC1 activity. Autophagy. 2022
Dec;18(12):2799-2816. doi: 10.1080/15548627.2022.2047481. Epub 2022 Mar 10.
PMID: 35266843; PMCID: PMC9673962.

37: Wu Y, Jiao H, Yue Y, He K, Jin Y, Zhang J, Zhang J, Wei Y, Luo H, Hao Z,
Zhao X, Xia Q, Zhong Q, Zhang J. Ubiquitin ligase E3 HUWE1/MULE targets
transferrin receptor for degradation and suppresses ferroptosis in acute liver
injury. Cell Death Differ. 2022 Sep;29(9):1705-1718. doi:
10.1038/s41418-022-00957-6. PMID: 35260822; PMCID: PMC9433446.

38: Shi Z, Gan G, Gao X, Chen F, Mi J. Kynurenine catabolic enzyme KMO regulates
HCC growth. Clin Transl Med. 2022 Feb;12(2):e697. doi: 10.1002/ctm2.697. PMID:
35184386; PMCID: PMC8858614.

39: Chen Q, Xin M, Wang L, Li L, Shen Y, Geng Y, Jiang H, Wang Y, Zhang L, Xu Y,
Hou Y, Liu J, Fan X. Inhibition of LDHA to induce eEF2 release enhances
thrombocytopoiesis. Blood. 2022 May 12;139(19):2958-2971. doi:
10.1182/blood.2022015620. PMID: 35176139.

40: Shu Z, Zeng J, Xia L, Cai H, Zhou A. Structural mechanism of VWF D'D3 dimer
formation. Cell Discov. 2022 Feb 15;8(1):14. doi: 10.1038/s41421-022-00378-2.
PMID: 35169124; PMCID: PMC8847404.

41: Zeng J, Shu Z, Liang Q, Zhang J, Wu W, Wang X, Zhou A. Structural basis of
von Willebrand factor multimerization and tubular storage. Blood. 2022 Jun
2;139(22):3314-3324. doi: 10.1182/blood.2021014729. PMID: 35148377.

42: He P, Zhang C, Ji Y, Ge MK, Yu Y, Zhang N, Yang S, Yu JX, Shen SM, Chen GQ.
Epithelial cells-enriched lncRNA SNHG8 regulates chromatin condensation by
binding to Histone H1s. Cell Death Differ. 2022 Aug;29(8):1569-1581. doi:
10.1038/s41418-022-00944-x. Epub 2022 Feb 9. PMID: 35140358; PMCID: PMC9345976.

43: Zhang Y, Cui Y, Li M, Cui K, Li R, Xie W, Liu L, Xiao Z. DNA-assembled
visible nanodandelions with explosive hydrogen-bond breakage achieving uniform
intra-tumor distribution (UITD)-guided photothermal therapy. Biomaterials. 2022
Mar;282:121381. doi: 10.1016/j.biomaterials.2022.121381. Epub 2022 Jan 26. PMID:
35123320.

44: Cui K, Zhang Y, Chen G, Cui Y, Wu W, Zhao N, Liu T, Xiao Z. Molecular
Regulation of Polymeric Raman Probes for Ultrasensitive Microtumor Diagnosis and
Noninvasive Microvessle Imaging. Small. 2022 Mar;18(12):e2106925. doi:
10.1002/smll.202106925. Epub 2022 Jan 29. PMID: 35092156.

45: Ma QX, Zhu WY, Lu XC, Jiang D, Xu F, Li JT, Zhang L, Wu YL, Chen ZJ, Yin M,
Huang HY, Lei QY. BCAA-BCKA axis regulates WAT browning through acetylation of
PRDM16. Nat Metab. 2022 Jan;4(1):106-122. doi: 10.1038/s42255-021-00520-6. Epub
2022 Jan 24. PMID: 35075301.

46: Zhang J, Qiu J, Zhou W, Cao J, Hu X, Mi W, Su B, He B, Qiu J, Shen L.
Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2
immunity. Nat Immunol. 2022 Feb;23(2):237-250. doi: 10.1038/s41590-021-01097-8.
Epub 2022 Jan 24. PMID: 35075279.

47: Li D, Xiong W, Wang Y, Feng J, He Y, Du J, Wang J, Yang M, Zeng H, Yang YG,
Wu N, Chen S, Dong Z. SLAMF3 and SLAMF4 are immune checkpoints that constrain
macrophage phagocytosis of hematopoietic tumors. Sci Immunol. 2022 Jan
21;7(67):eabj5501. doi: 10.1126/sciimmunol.abj5501. Epub 2022 Jan 21. PMID:
35061505.

48: Shi L, Yang Y, Li M, Li C, Zhou Z, Tang G, Wu L, Yao Y, Shen X, Hou Z, Jia
H. LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual
mechanism in oral carcinogenesis. Mol Ther. 2022 Apr 6;30(4):1564-1577. doi:
10.1016/j.ymthe.2022.01.003. Epub 2022 Jan 17. PMID: 35051616; PMCID:
PMC9077312.

49: Yin H, Jing B, Xu D, Guo W, Sun B, Zhang J, Liao Y, Song H, Wang T, Liu S,
Kuang Y, Hu M, Li K, Zhang S, Zhang H, Xu J, Li X, Du J, Wu Y, Wu Y, Wang Q, Yao
F, Chin YE, Zhou BP, Deng J. Identification of Active Bronchioalveolar Stem
Cells as the Cell of Origin in Lung Adenocarcinoma. Cancer Res. 2022 Mar
15;82(6):1025-1037. doi: 10.1158/0008-5472.CAN-21-2445. PMID: 35045987.

50: Hao Q, Huang Z, Li Q, Liu D, Wang P, Wang K, Li J, Cao W, Deng W, Wu K, Su
R, Liu Z, Vadgama J, Wu Y. A Novel Metabolic Reprogramming Strategy for the
Treatment of Diabetes-Associated Breast Cancer. Adv Sci (Weinh). 2022
Feb;9(6):e2102303. doi: 10.1002/advs.202102303. Epub 2022 Jan 12. PMID:
35023320; PMCID: PMC8867195.

51: Guo L, Dai W, Xu Z, Liang Q, Miller ET, Li S, Gao X, Baldwin MW, Chai R, Li
Q. Evolution of Brain-Expressed Biogenic Amine Receptors into Olfactory Trace
Amine-Associated Receptors. Mol Biol Evol. 2022 Mar 2;39(3):msac006. doi:
10.1093/molbev/msac006. Erratum in: Mol Biol Evol. 2022 May 3;39(5): PMID:
35021231; PMCID: PMC8890504.

52: Zhang Y, Zhang F, Wang Z, Wu S, Tian W. scMAGIC: accurately annotating
single cells using two rounds of reference-based classification. Nucleic Acids
Res. 2022 May 6;50(8):e43. doi: 10.1093/nar/gkab1275. PMID: 34986249; PMCID:
PMC9071478.

53: Yu Z, Yang W, He X, Chen C, Li W, Zhao L, Liu L, Liu J, Xie L, Zhang Y,
Zheng J. Endothelial cell-derived angiopoietin-like protein 2 supports
hematopoietic stem cell activities in bone marrow niches. Blood. 2022 Mar
10;139(10):1529-1540. doi: 10.1182/blood.2021011644. PMID: 34929029; PMCID:
PMC9015010.

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