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9. Demydchuk, M; Hill, CH; Zhou, AW; Bunkoczi, G; Stein, PE; Marchesan, D; Deane, JE; Read, RJ.Insights into Hunter syndrome from the structure of iduronate-2-sulfatase.NATURE COMMUNICATIONS.12.121
10. Boto, C; Quartin, E; Cai, YJ; Martin-Lorenzo, A; Cenador, MBG; Pinto, S; Gupta, R; Enver, T; Sanchez-Garcia, I; Hong, DL; das Neves, RP; Ferreira, L.Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation.NATURE COMMUNICATIONS.12.121
11. Wu, YD; Wang, Y; Lin, YW; Liu, YJ; Wang, YF; Jia, JH; Singh, P; Chi, YI; Wang, C; Dong, CF; Li, W; Tao, M; Napier, D; Shi, QY; Deng, J; Evers, BM; Zhou, BHP.Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.NATURE COMMUNICATIONS.12.121
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16. Xia, F; Zhang, Y; Xie, L; Jiang, H; Zeng, H; Chen, C; Liu, L; He, X; Hao, X; Fang, X; Liu, X; Zhang, F; Gu, H; Wan, J; Cheng, Y; Zhang, CC; Chen, GQ; Lu, Y; Yu, Z; Zheng, J.B7-H4 enhances the differentiation of murine leukemia-initiating cells via the PTEN/AKT/RCOR2/RUNX1 pathways.LEUKEMIA.8.665
17. Liu, TH; Tang, YJ; Huang, Y; Wang, L; Guo, XL; Mi, JQ; Liu, LG; Zhu, H; Zhang, Y; Chen, L; Liu, X; Zhang, LH; Ye, QJ; Li, BS; Tang, JY; Ford, A; Enver, T; Liu, F; Chen, GQ; Hong, DL.Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin.LEUKEMIA.8.665
18. Cao, Y; Lin, SH; Wang, YB; Chin, YE; Kang, L; Mi, J.Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling.THERANOSTICS.8.579
19. Jiang, Y; Cao, Y; Wang, YB; Li, W; Liu, XY; Lv, YX; Li, XL; Mi, J.Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis.THERANOSTICS.8.579
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21. Jia, H; Song, L; Cong, Q; Wang, J; Xu, H; Chu, Y; Li, Q; Zhang, Y; Zou, X; Zhang, C; Chin, YE; Zhang, X; Li, Z; Zhu, K; Wang, B; Peng, H; Hou, Z.The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network.ONCOGENE.7.971
22. Hu, Y; Li, D; Wu, AY; Qiu, XD; Di, W; Huang, L; Qiu, LH.TWEAK-stimulated macrophages inhibit metastasis of epithelial ovarian cancer via exosomal shuttling of microRNA.CANCER LETTERS.7.36
23. Wang, YH; Fu, L; Cui, MQ; Wang, YB; Xu, Y; Li, ML; Mi, J.Amino acid transporter SLC38A3 promotes metastasis of non-small cell lung cancer cells by activating PDK1.CANCER LETTERS.7.36
24. Lu, SY; Zhang, J.Designed covalent allosteric modulators: an emerging paradigm in drug discovery.DRUG DISCOVERY TODAY.7.321
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26. Zhang, F; Wei, HD; Wang, XX; Bai, Y; Wang, PL; Wu, JW; Jiang, XY; Wang, YG; Cai, HY; Xu, T; Zhou, AW.Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade.CELL DISCOVERY.6.255
27. Tang, J; Zhan, MN; Yin, QQ; Zhou, CX; Wang, CL; Wo, LL; He, M; Chen, GQ; Zhao, Q.Impaired p65 degradation by decreased chaperone-mediated autophagy activity facilitates epithelial-to-mesenchymal transition.ONCOGENESIS.6.119
28. Zhao, X; Deng, R; Wang, Y; Zhang, H; Dou, J; Li, L; Du, Y; Chen, R; Cheng, J; Yu, J.Twist1/Dnmt3a and miR186 establish a regulatory circuit that controls inflammation-associated prostate cancer progression.ONCOGENESIS.6.119
29. Wang, YB; Gan, GF; Wang, BC; Wu, JL; Cao, Y; Zhu, D; Xu, Y; Wang, XN; Han, HX; Li, XL; Ye, M; Zhao, JM; Mi, J.Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy.EBIOMEDICINE.5.736
30. Wang, J; Qian, S; Liu, XY; Xu, LY; Miao, XC; Xu, ZY; Cao, LY; Wang, HL; Jiang, XQ.M2 macrophages contribute to osteogenesis and angiogenesis on nanotubular TiO2 surfaces.JOURNAL OF MATERIALS CHEMISTRY B.5.344
31. Guo, XL; Chu, L; Ke, F; Mu, LL; Li, Z; Cai, JJ; Li, HF; Hong, DL.Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.ONCOTARGET.5.168
32. Xia, L; Qin, K; Wang, XR; Wang, XL; Zhou, AW; Chen, GQ; Lu, Y.Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells.ONCOTARGET.5.168
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35. Wang, J; Yin, MZ; Zhao, KW; Ke, F; Jin, WJ; Guo, XL; Liu, TH; Liu, XY; Gu, H; Yu, XM; Li, Z; Mu, LL; Hong, DL; Chen, J; Chen, GQ.APC/C is essential for hematopoiesis and impaired in aplastic anemia.ONCOTARGET.5.168
36.Wei, HD; Cai, HY; Jin, YH; Wang, PL; Zhang, QQ; Lin, YH; Wang, WX; Cheng, JK; Zeng, NY; Xu, T; Zhou, AW.Structural basis of a novel heterodimeric Fc for bispecific antibody production.ONCOTARGET.5.168
37. Bawa-Khalfe, T; Yang, FM; Ritho, J; Lin, HK; Cheng, J; Yeh, ETH.SENP1 regulates PTEN stability to dictate prostate cancer development.ONCOTARGET.5.168
38. Sun, BB; Guo, WZ; Hu, S; Yao, F; Yu, KK; Xing, J; Wang, RH; Song, HY; Liao, YL; Wang, T; Jiang, PF; Han, BH; Deng, J.Gprc5a-knockout mouse lung epithelial cells predicts ceruloplasmin, lipocalin 2 and periostin as potential biomarkers at early stages of lung tumorigenesis.ONCOTARGET.5.168
39. Zhang, L; Li, L; Gao, GL; Wei, GG; Zheng, YS; Wang, CM; Gao, N; Zhao, YL; Deng, J; Chen, HQ; Sun, JL; Li, DL; Zhang, XL; Liu, MY.Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress.INTERNATIONAL JOURNAL OF CANCER.5.145
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41. Ni, D; Song, K; Zhang, J; Lu, S.Molecular Dynamics Simulations and Dynamic Network Analysis Reveal the Allosteric Unbinding of Monobody to H-Ras Triggered by R135K Mutation.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.4.556
42. Cai, HY; Wang, T; Yang, Z; Xu, ZJ; Wang, GM; Wang, HY; Zhu, WL; Chen, KX.Combined Virtual Screening and Substructure Search for Discovery of Novel FABP4 Inhibitors.JOURNAL OF CHEMICAL INFORMATION AND MODELING.4.549
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44. Xu, JD; Jiang, HS; Wei, TD; Zhang, KY; Wang, XW; Zhao, XF; Wang, JX.Interaction of the Small GTPase Cdc42 with Arginine Kinase Restricts White Spot Syndrome Virus in Shrimp .JOURNAL OF VIROLOGY.4.501
45. Xia, FZ; Wang, NJ; Han, B; Li, Q; Chen, Y; Zhu, CF; Chen, YC; Pu, XQ; Cang, Z; Zhu, CX; Lu, M; Men, Y; Guo, H; Chen, C; Lin, DP; Zheng, JK; Kuang, L; Tu, WP; Li, B; Hu, L; Shen, ZJ; Lu, YL.Hypothalamic-Pituitary-Gonadal Axis on Aging Men and Women: Increasing Total Testosterone in Aging Men.NEUROENDOCRINOLOGY.4.271
46. Lei, H; Shan, HZ; Wu, YL.Targeting deubiquitinating enzymes in cancer stem cells.CANCER CELL INTERNATIONAL.4.175
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48. Xiao, XH; Li, HL; Jin, HZ; Jin, J; Yu, M; Ma, CM; Tong, Y; Zhou, L; Lei, H; Xu, HZ; Zhang, WD; Liu, W; Wu, YL.Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma.CELL DEATH & DISEASE.4.114
49. Jin, W; Liao, XD; Lv, YP; Pang, Z; Wang, YM; Li, QF; Liao, YH; Ye, Q; Chen, GQ; Zhao, KW; Huang, L.MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner.CELL DEATH & DISEASE.4.114
50. Fu, RJ; He, W; Wang, XB; Li, L; Zhao, HB; Liu, XY; Pang, Z; Chen, GQ; Huang, L; Zhao, KW.DNMT1-maintained hypermethylation of Kruppel-like factor 5 involves in the progression of clear cell renal cell carcinoma.CELL DEATH & DISEASE.4.114
51. Liu, S; Liu, HY; Qin, R; Shu, Y; Liu, ZD; Zhang, PH; Duan, CW; Hong, DL; Yu, J; Zou, L.The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by beta-Arrestin1 binding with P300-Sp1 to regulate hTERT transcription.CELL DEATH & DISEASE.4.114
52. Zhan, MN; Yu, XT; Tang, J; Zhou, CX; Wang, CL; Yin, QQ; Gong, XF; He, M; He, JR; Chen, GQ; Zhao, Q.MicroRNA-494 inhibits breast cancer progression by directly targeting PAK1.CELL DEATH & DISEASE.4.114
53. Yang, XT; Huang, GH; Li, HJ; Sun, ZL; Xu, NJ; Feng, DF.Rac1 Guides Porf-2 to Wnt Pathway to Mediate Neural Stem Cell Proliferation.FRONTIERS IN MOLECULAR NEUROSCIENCE.4.057
54. Yu, TT; Zuo, Y; Cai, R; Huang, X; Wu, S; Zhang, CX; Chin, YE; Li, DD; Zhang, ZN; Xia, NS; Wang, Q; Shen, H; Yao, XB; Zhang, ZY; Xue, S; Shen, L; Cheng, JK.SENP1 regulates IFN-gamma-STAT1 signaling through STAT3-SOCS3 negative feedback loop.JOURNAL OF MOLECULAR CELL BIOLOGY.4
55. Yang, XY; Zhang, X; Huang, M; Song, K; Li, XF; Huang, ML; Meng, LH; Zhang, J.New Insights into PI3K Inhibitor Design using X-ray Structures of PI3K alpha Complexed with a Potent Lead Compound.SCIENTIFIC REPORTS.3.998
56. An, XF; Zhang, L; Yuan, YG; Wang, B; Yao, QM; Li, L; Zhang, JS; He, M; Zhang, JN.Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expression.SCIENTIFIC REPORTS.3.998
57. Liu, YX; Hu, YY; E, QK; Zuo, J; Yang, L; Liu, W.Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin.SCIENTIFIC REPORTS.3.998
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59. Liu, SL; Liu, Z; Zhang, LD; Zhu, HQ; Guo, JH; Zhao, M; Wu, YL; Liu, F; Gao, FH.GSK3 beta-dependent cyclin D1 and cyclin E1 degradation is indispensable for NVP-BEZ235 induced G0/G1 arrest in neuroblastoma cells.CELL CYCLE.3.699
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62. Wang, YH; Jiang, LR; Mo, X; Lan, Y; Yang, X; Liu, XY; Zhang, J; Zhu, L; Liu, JL; Wu, XL.Megakaryocytic Smad4 Regulates Platelet Function through Syk and ROCK2 Expression.MOLECULAR PHARMACOLOGY.3.664
63. Liu, YX; Dong, WB; Shao, J; Wang, YB; Zhou, MY; Sun, HP.Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway.FRONTIERS IN PHYSIOLOGY.3.367
64. Zhang, L; An, XF; Ruan, X; Huang, DD; Zhou, L; Xue, H; Lu, LM; He, M.Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy.FRONTIERS IN PHYSIOLOGY.3.367
65. Zou, YF; Wen, D; Zhao, Q; Shen, PY; Shi, H; Zhao, Q; Chen, YX; Zhang, W.Urinary MicroRNA-30c-5p and MicroRNA-192-5p as potential biomarkers of ischemia-reperfusion-induced kidney injury.EXPERIMENTAL BIOLOGY AND MEDICINE.3.139
66. Yan, JS; Li, YD; Liu, SH; Yin, QQ; Liu, XY; Xia, L; Lu, Y.The t(8;21) fusion protein RUNX1-ETO downregulates PKM2 in acute myeloid leukemia cells.LEUKEMIA & LYMPHOMA.2.969
67. Yu, WJ; Chen, YB; Xiang, RF; Xu, WB; Wang, Y; Tong, J; Zhang, N; Wu, YL; Yan, H.Novel phosphatidylinositol 3-kinase inhibitor BKM120 enhances the sensitivity of multiple myeloma to bortezomib and overcomes resistance.LEUKEMIA & LYMPHOMA.2.969
68. Mao, JY; Sun, JT; Yang, K; Shen, WF; Lu, L; Zhang, RY; Tong, XM; Liu, Y.Serum amyloid A enrichment impairs the anti-inflammatory ability of HDL from diabetic nephropathy patients.JOURNAL OF DIABETES AND ITS COMPLICATIONS.2.781
69. Yu, T; Su, XB; Pan, Y; Zhuang, HY.Receptor-transporting protein (RTP) family members play divergent roles in the functional expression of odorant receptors .PLOS ONE.2.74
70. Lei, H; Li, XY; Jing, B; Xu, HZ; Wu, YL.Human S100A7 Induces Mature Interleukin 1 alpha Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis.PLOS ONE.2.74
71. Mu, LL; Ke, F; Guo, XL; Cai, JJ; Hong, DL.Neoplasms in the bone marrow niches: disturbance of the microecosystem.INTERNATIONAL JOURNAL OF HEMATOLOGY.2.245
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